US overdose deaths fell 27% last year, the largest one-year decline ever seen

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By MIKE STOBBE and GEOFF MULVIHILL, Associated Press

There were 30,000 fewer U.S. drug overdose deaths in 2024 than the year before — the largest one-year decline ever recorded.

An estimated 80,000 people died from overdoses last year, according to provisional Centers for Disease Control and Prevention data released Wednesday. That’s down 27% from the 110,000 in 2023.

The CDC has been collecting comparable data for 45 years. The previous largest one-year drop was 4% in 2018, according to the agency’s National Center for Health Statistics.

All but two states saw declines last year, with Nevada and South Dakota seeing small increases. Some of the biggest drops were in Ohio, West Virginia and other states that have been hard-hit in the nation’s decades-long overdose epidemic.

Experts say more research needs to be done to understand what drove the reduction, but they mention several possible factors. Among the most cited:

Increased availability of the overdose-reversing drug naloxone.
Expanded addiction treatment.
Shifts in how people use drugs.
The growing impact of billions of dollars in opioid lawsuit settlement money.
The number of at-risk Americans is shrinking, after waves of deaths in older adults and a shift in teens and younger adults away from the drugs that cause most deaths.

Still, annual overdose deaths are higher than they were before the COVID-19 pandemic. In a statement, the CDC noted that overdoses are still the leading cause of death for people 18-44 years old, “underscoring the need for ongoing efforts to maintain this progress.”

Some experts worry that the recent decline could be slowed or stopped by reductions in federal funding and the public health workforce, or a shift away from the strategies that seem to be working.

“Now is not the time to take the foot off the gas pedal,” said Dr. Daniel Ciccarone, a drug policy expert at the University of California, San Francisco.

The provisional numbers are estimates of everyone who died of overdoses in the U.S., including noncitizens. That data is still being processed, and the final numbers can sometimes differ a bit. But it’s clear that there was a huge drop last year.

Experts note that there have been past moments when U.S. overdose deaths seemed to have plateaued or even started to go down, only to rise again. That happened in 2018.

But there are reasons to be optimistic.

Naloxone has become more widely available, in part because of the introduction of over-the-counter versions that don’t require prescriptions.

Meanwhile, drug manufacturers, distributors, pharmacy chains and other businesses have settled lawsuits with state and local governments over the painkillers that were a main driver of overdose deaths in the past. The deals over the last decade or so have promised about $50 billion over time, with most of it required to be used to fight addiction.

Another settlement that would be among the largest, with members of the Sackler family who own OxyContin maker Purdue Pharma agreeing to pay up to $7 billion, could be approved this year.

The money, along with federal taxpayer funding, is going to a variety of programs, including supportive housing and harm reduction efforts, such as providing materials to test drugs for fentanyl, the biggest driver of overdoses now.

But what each state will do with that money is currently at issue. “States can either say, ‘We won, we can walk away’” in the wake of the declines or they can use the lawsuit money on naloxone and other efforts, said Regina LaBelle, a former acting director of the Office of National Drug Control Policy. She now heads an addiction and public policy program at Georgetown University.

President Donald Trump’s administration views opioids as largely a law enforcement issue and as a reason to step up border security. That worries many public health leaders and advocates.

“We believe that taking a public health approach that seeks to support — not punish — people who use drugs is crucial to ending the overdose crisis,” said Dr. Tamara Olt, an Illinois woman whose 16-year-old son died of a heroin overdose in 2012. She is now executive director of Broken No Moore, an advocacy organization focused on substance use disorder.

Olt attributes recent declines to the growing availability of naloxone, work to make treatment available, and wider awareness of the problem.

Kimberly Douglas, an Illinois woman whose 17-year-old son died of an overdose in 2023, credited the growing chorus of grieving mothers. “Eventually people are going to start listening. Unfortunately, it’s taken 10-plus years.”

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.

American Eagle tumbles after pulling financial guidance for 2025

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By MICHELLE CHAPMAN, Associated Press Business Writer

Shares of American Eagle Outfitters are tumbling before Wednesday’s opening bell after the retailer withdrew its financial outlook for the year citing “macro uncertainty” and said it would write down $75 million in spring and summer merchandise.

American Eagle said late Tuesday that it expects first-quarter revenue to slide 5%, or more than $1 billion. Same-store sales, a key gauge of a retailer’s health, are projected to fall about 3%.

The Pittsburgh company foresees a first-quarter adjusted operating loss of about $68 million due to the inventory write-down as well as heavier spending on promotions.

The company’s stock slumped 6% at the opening bell Wednesday.

CEO and Executive Chairman Jay Schottenstein said the retailer is unhappy with its execution during the first quarter.

“Merchandising strategies did not drive the results we anticipated, leading to higher promotions and excess inventory,” Schottenstein said in a statement. “As a result, we have taken an inventory write down on spring and summer goods.”

A large number of companies across multiple sectors have withdrawn financial guidance this year as a U.S.-led trade war creates uncertainty about costs for imported goods. The massive shift in U.S. trade policy has unsettled consumers as well and there are early signs that may Americans are becoming more judicious about spending.

American Eagle cited macro uncertainty as it pulled it 2025 financial guidance as it reviews future plans.

Schottenstein said American Eagle is in a better position for the second quarter, with inventory more aligned to sales trends.

“Our teams continue to work with urgency to strengthen product performance, while improving our buying principles,” he said.

Paul Lejuez of Citi Investment Research said in a note to clients that he expects American Eagle to aggressively cut its inventory plans for the second half of the year and to focus on cost control.

“With the demand picture less clear and margin pressure from tariffs, promos and freight, American Eagle is in a tough spot to navigate the current uncertain environment,” he wrote.

American Eagle reports first-quarter financial results on May 29.

Trump’s Middle East visit comes as his family deepens its business, crypto ties in the region

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By WILL WEISSERT, Associated Press

WASHINGTON (AP) — It’s not just the “gesture” of a $400 million luxury plane that President Donald Trump says he’s smart to accept from Qatar. Or that he effectively auctioned off the first destination on his first major foreign trip, heading to Saudi Arabia because the kingdom was ready to make big investments in U.S. companies.

It’s not even that the Trump family has fast-growing business ties in the Middle East that run deep and offer the potential of vast profits.

President Donald Trump and His Royal Highness, Mohammed bin Salman al Saud, Crown Prince and Prime Minister, Kingdom of Saudi Arabia, tour the Diriyah/At-Turaif UNESCO World Heritage Site, Tuesday, May 13, 2025, in Riyadh, Saudi Arabia. (AP Photo/Alex Brandon)

Instead, it’s the idea that the combination of these things and more — deals that show the close ties between a family whose patriarch oversees the U.S. government and a region whose leaders are fond of currying favor through money and lavish gifts — could cause the United States to show preferential treatment to Middle Eastern leaders when it comes to American affairs of state.

Before Trump began his visit to Saudi Arabia, Qatar and the United Arab Emirates, his sons Eric and Donald Jr. had already traveled the Middle East extensively in recent weeks. They were drumming up business for The Trump Organization, which they are running in their father’s stead while he’s in the White House.

Eric Trump announced plans for an 80-story Trump Tower in Dubai, the UAE’s largest city. He also attended a recent cryptocurrency conference there with Zach Witkoff, a founder of the Trump family crypto company, World Liberty Financial, and son of Trump’s do-everything envoy to the Mideast, Steve Witkoff.

“We are proud to expand our presence in the region,” Eric Trump said last month in announcing that Trump Tower Dubai was set to start construction this fall.

The presidential visit to the region, as his children work the same part of the world for the family’s moneymaking opportunities, puts a spotlight on Trump’s willingness to embrace foreign dealmaking while in the White House, even in the face of growing concerns that doing so could tempt him to shape U.S. foreign policy in ways that benefit his family’s bottom line.

Nowhere is the potential overlap more prevalent than in the Middle East

The Trump family’s business interests in the region include a new deal to build a luxury golf resort in Qatar, partnering with Qatari Diar, a real estate company backed by that country’s sovereign wealth fund. The family is also leasing its brand to two new real estate projects in Riyadh, Saudi Arabia’s capital, in partnership with Dar Global, a London-based luxury real estate developer and subsidiary of private Saudi real estate firm Al Arkan.

The Trump Organization has similarly partnered with Dar Global on a Trump Tower set to be built in Jeddah, Saudi Arabia, and an upcoming Trump International Hotel and luxury golf development in neighboring Oman.

During the crypto conference, a state-backed investment company in Abu Dhabi announced it had chosen USD, World Liberty Financial’s stablecoin, to back a $2 billion investment in Binance, the world’s largest cryptocurrency exchange. Critics say that allows Trump family-aligned interests to essentially take a cut of each dollar invested.

“I don’t know anything about it,” Trump said when asked by reporters about the transaction on Wednesday.

President Donald Trump speaks at the Saudi-U.S. Investment Forum at the King Abdulaziz International Conference Center in Riyadh, Saudi Arabia, Tuesday, May 13, 2025. (AP Photo/Alex Brandon)

Then there’s the Saudi government-backed LIV Golf, which has forged close business relationships with the president and hosted tournaments at Trump’s Doral resort in South Florida.

“Given the extensive ties between LIV Golf and the PIF, or between Trump enterprises more generally and the Gulf, I’d say there’s a pretty glaring conflict of interest here,” said Jon Hoffman, a research fellow in defense and foreign policy at the libertarian think tank the Cato Institute. He was referring to Saudi Arabia’s Public Investment Fund, which has invested heavily in everything from global sports giants to video game maker Nintendo with the aim of diversifying the kingdom’s economy beyond oil.

Trump said he did not talk about LIV Golf during his visit in Saudi Arabia.

The president announced in January a $20 billion investment for U.S. data centers promised by DAMAC Properties, an Emirati company led by billionaire Dubai developer Hussain Sajwani. Trump bills that as benefiting the country’s technological and economic standing rather than his family business. But Sajwani was a close business partner of Trump and his family since long before the 2016 election.

White House bristles at conflict of interest concerns

Asked before he left for the Middle East if Trump might use the trip to meet with people tied to his family’s business, White House press secretary Karoline Leavitt said it was “ridiculous” to “suggest that President Trump is doing anything for his own benefit.”

“The president is abiding by all conflict of interest laws,” she said.

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Administration officials have brushed off such concerns about the president’s policy decisions bleeding into the business interests of his family by noting that Trump’s assets are in a trust managed by his children. A voluntary ethics agreement released by The Trump Organization also bars the firm from striking deals directly with foreign governments.

But that same agreement still allows deals with private companies abroad. In Trump’s first term, the organization released an ethics pact prohibiting deals with both foreign governments and foreign companies.

The president, according to the second-term ethics agreement, isn’t involved in any day-to-day decision-making for the family business. But his political and corporate brands remain inextricably linked.

“The president is a successful businessman,” Leavitt said, “and I think, frankly, that it’s one of the many reasons that people reelected him back to this office.”

Timothy P. Carney, senior fellow at the conservative American Enterprise Institute, said he doesn’t want to see U.S. foreign policy being affected by Trump’s feelings about how other countries have treated his family’s business.

“Even if he’s not running the company, he profits when the company does well,” Carney said. “When he leaves the White House, the company is worth more, his personal wealth goes up.”

Promises of US investment shaped Trump’s trip

His family business aside, the president wasn’t shy about saying he’d shape the itinerary of his first extended overseas trip on quid pro quo.

Trump’s first stop was Saudi Arabia, just as during his first term. He picked the destination after he said the kingdom had pledged to spend $1 trillion on U.S. companies over four years. The White House has since announced that the actual figure is $600 billion. How much of that will actually be new investment — or come to fruition — remains to be seen.

The president is also stopping in the UAE, which has pledged $1.4 trillion in U.S. investments over the next 10 years, and in Qatar, where Trump says accepting the gift of a Boeing 747 from the ruling family is a no-brainer, dismissing security and ethical concerns raised by Democrats and even some conservatives.

Trump’s Middle East business ties predate his presidencies

Trump’s first commercial foray in the Middle East came in 2005, during just his second year of starring on “The Apprentice.” A Trump Tower Dubai project was envisioned as a tulip-shaped hotel to be perched on the city’s manmade island shaped like a palm tree.

It never materialized.

Instead, February 2017 saw the announced opening of Trump International Golf Club Dubai, with Sajwani’s DAMAC Properties. Just a month earlier, Trump had said that Sajwani had tried to make a $2 billion deal with him, “And I turned it down.”

“I didn’t have to turn it down, because as you know, I have a no-conflict situation because I’m president,” Trump said then.

This January, there was a beaming Sajwani standing triumphantly by Trump’s side at Trump’s Mar-a-Lago estate in Florida, to announce DAMAC’s investment in U.S. data centers.

“It’s been amazing news for me and my family when he was elected in November,” Sajwani said. “For the last four years, we’ve been waiting for this moment.”

Trump administration rescinds curbs on AI chip exports to foreign markets

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NEW YORK (AP) — After a week of promises to alter the policy, the U.S. Department of Commerce has rescinded a Biden-era rule due to take effect Thursday that placed limits on the number of artificial intelligence chips that could be exported to certain international markets without federal approval.

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“These new requirements would have stifled American innovation and saddled companies with burdensome new regulatory requirements,” the Commerce Department stated in its guidance.

The Biden administration had established the export framework in an attempt to balance national security concerns about the technology with the economic interests of producers and other countries. While the United States had already restricted exports to adversaries such as China and Russia, some of those controls had loopholes and the rule would have set limits on a much broader group of countries.

Commerce Undersecretary Jeffery Kessler said Tuesday that the Trump administration work to replace the now-rescinded rule.

“The Trump Administration will pursue a bold, inclusive strategy to American AI technology with trusted foreign countries around the world, while keeping the technology out of the hands of our adversaries.”