Lauren Liebhaber | (TNS) The Charlotte Observer

A “close cousin” of the dangerous strain of E. coli could provide a new way to treat urinary tract infections, researchers said.

Researchers from Texas A&M are working to build a device that uses harmless strains of E. coli, first discovered in the 1970s, to inhibit the growth of bad bacteria that cause UTIs, according to a Sept. 17 news release from the university.

According to researchers, the good strain of E. coli is beneficial because it uses up all the nutrients that bad E. coli, and other UTI-causing bacteria such as Staphylococcus, need to survive.

“The urinary tract becomes so populated by the good strain that the harmful bacteria are unable to grow, preventing UTIs,” researchers said in the release.

The goal is to use a hydrogel device, similar to a contact lens, loaded with living E. coli that “floats freely in the bladder and slowly releases” beneficial bacteria into the urinary tract, preventing bad bacteria from thriving, according to researchers.

Constant use of antibiotics among people prone to frequent UTIs, including those with spinal cord injuries and women in menopause, can lead to long-term “negative effects on the gut microbiome and overall health,” researchers said.

“Using ‘good’ bacteria to fight ‘bad’ bacteria opens up all kinds of new treatment and prevention possibilities and not just for UTIs,” associate professor Dr. Sarguru Subash said in the release.

The project is a collaboration between researchers from Texas A&M’s College of Veterinary Medicine and Biomedical Sciences and the College of Engineering.

SANTA MARIA, Calif. (AP) — An explosive device that authorities said was intentionally set has injured two people at a California courthouse on Wednesday, authorities said.

One person of interest was detained following the blast reported shortly after 8:45 a.m. at the Santa Maria Courthouse in Santa Maria, sheriff’s officials said. The small city of about 110,000 people in Santa Barbara County is in California’s central coast region.

“We have two reports of non-life-threatening injuries. One person of interest detained immediately. Scene remains active. Please continue to avoid the area,” Santa Barbara County Sheriff Public Information Officer Raquel Zick said on the social platform X.

Zick later said the person detained was a man and the blast came from “an intentionally set” explosive device.

Shane Mellon told KSBY-TV that he was at the courthouse when he heard what sounded like chairs falling over.

“It was a loud bang,” he said, adding the bailiff escorted him and others out.

Mellon said he saw what looked like a sweater smoldering and a man screaming while four or five people got on top of him, trying to keep him restrained.

“I think this could have been way worse than it was if not for the deputies just jumping on top of that guy,” Mellon said.

A spokesperson for the Santa Barbara County Sheriff’s Department declined to immediately provide additional information.

The office of California Gov. Gavin Newsom said it was monitoring the situation and coordinating with local law enforcement.

The website for the Superior Court in Santa Barbara County said the courthouse complex was closed for the day and all courtroom calendars were canceled. Phone and email messages were left for Darrel Parker, the court’s executive officer.

Santa Maria City Hall, which is located near the courthouse, was closed Wednesday due to the ongoing investigation, said Mark van de Kamp, a spokesperson for the city. So were other nearby city offices in addition to branch libraries that depend on the city’s main library for support, he said.

The courthouse holds state and county courts in the city of Santa Maria, which is about 150 miles (240 kilometers) northwest of Los Angeles. Two decades ago, the courthouse was where Michael Jackson was tried and acquitted of sexual abuse.

Which trail running shoe is best?

Trail running allows those who enjoy the hobby to get needed exercise while enjoying the outdoors, but it’s easier to appreciate and enjoy something when you are comfortable. Purchasing the best trail running shoe for both comfort and durability will make all the difference in long-distance runs through rugged terrain.

When purchasing a good pair of trail running shoes, consider the material, traction and size of the shoe. A top choice, the Saucony Women’s Peregrine 11 Trail Running Shoe, is a favorite among many due to its durable make and light weight.

What to know before you buy a trail running shoe

Material

Trail running shoes are made with materials that can withstand more wear and tear than normal running shoes due to the rough terrains they encounter. Mesh fabric is breathable and helps prevent rips in the shoe while the presence of rubber lugs in the outsole provide better off-road traction.

Traction

The traction of a trail shoe is specifically designed to grip onto rugged terrain and allow for convenient runs through dirt, mud, gravel and roots. Traction can determine other factors, such as balance and where you are able to hike. If you are hiking an icy winter trail and a shoe does not have grip or traction, you will lack stability.

Size

Get your foot sized before purchasing a good pair of trail running shoes. Shoes that are too small can cause blisters and foot pain. Your left foot and your right foot may not be the same size and can differ by as much as a full shoe size. When you have found the right-sized shoe for each foot, the trail run will be more comfortable.

What to look for in a quality trail running shoe

Cushion

In general, shoes with built-in protection and cushioning provide more comfort and support than other options. If you do not run long distances and are most concerned with comfort, look into a thicker outsole. If you run a lot, look for a 0mm drop heel for a greater range of motion and added comfort.

Outsole support

The soles of trail running shoes are designed to grip an uneven trail surface. Large lugs, teeth and a stickier rubber offer better traction to get you over and through dirt, mud, rocks, plants and all sorts of other natural debris. Most trail running shoes have rock plates made out of hard plastic located in the midsole area that protect your foot from rocks and sharp sticks.

Weather protection

A good trail running shoe has enough traction to make it easier to run in slick or rough conditions, but it is often not waterproof. Waterproof trail-running shoes are usually not needed, even if the area you’re running in is wet or rain is in the forecast. Waterproof shoes tend to trap water inside the shoe, causing the feet to overheat and sweat. It’s important that the shoe is breathable but not waterproof.

How much you can expect to spend on a trail running shoe

Runners on a budget can find trail running shoes between $70 and $80, and midrange shoes usually are $90-$100. Premium trail running shoes that include all the best features cost $100-$130.

Trail running shoe FAQ

What’s the difference between a trail shoe and a road shoe?

A. Trail running shoes are designed for tough, rugged, rocky and natural surfaces. Due to the various terrains they will be used on, they are more durable and heavier than an everyday running shoe. Road shoes are designed for paved paths with very few environmental factors, meaning they don’t have the extra grip or durability needed for the rough terrain of natural trails in the great outdoors.

Can you wear road shoes to run trails?

A. This largely depends on how often you run on trails. If you’re a runner who constantly runs on trails, road shoes won’t last as long and can quickly be ruined. Consider purchasing shoes specifically for trail hiking to protect your feet and ankles, make your shoes last longer and be the most comfortable on your run.

What’s the best trail running shoe to buy?

Top trail running shoe

Saucony Women’s Peregrine 11 Trail Running Shoe

What you need to know: These shoes are designed with aggressive rubber lugs that conform to and dig into various terrains.

What you’ll love: The rock plate ensures additional protection for pushing uphill and driving downhill when running trails. The mesh makes them ultra light and durable.

What you should consider: Some users have experienced arch pain and blisters during long runs.

Top trail running shoe for the money

Inov-8 Women’s Terraultra G 270 Trail Running Shoes

What you need to know: These shoes feature durability, comfort and grip for long-distance runs.

What you’ll love: The 0mm drop between heel and toe allows the greatest range of motion in the ankle. The shoe is very cushioned, with a wider-fitting toe box and an ultra-thin outsole, which is great for various terrain and traction.

What you should consider: The extra cushion adds weight to the shoes, and some wearers noticed foot pain after running.

Worth checking out

La Sportiva Men’s Bushido II Running Shoe

What you need to know: These trail running shoes combine stability and comfort with great traction and a sticky outsole.

What you’ll love: This product’s tongue and heel are padded to stay in place like a no-slip sock and provide good breathability.

What you should consider: Some users claim these shoes aren’t fit for rough terrain and run small.

Prices listed reflect time and date of publication and are subject to change.

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