Competition director Eric Zandona said 290 whiskeys were entered into this year’s contest, though that number includes recipes from across the world. In all, 700 spirits were entered into the competition, which started in 2007.
Judges evaluate flights of spirits based on their overall quality and taste, assigning each one a score from 0 to 100. Spirits that score 90 points or more earn a gold medal, and judges can award a double gold if they believe the liquor is exemplary in its style (i.e. bourbon, single malt, rye, etc.). Those that earn both gold and double gold medals get considered for the “best in class” honor. Only one gets crowned the greatest among its category (i.e. vodka, gin, whiskey, agave, etc.).
Taluna’s spirit rose above all other whiskeys, across all the different styles, that were made stateside. The distillery is unique in that it uses a pot still method, similar to many Irish whiskeys. That method requires the use of a copper pot still and a distinct mash bill, which is half malted barley and half unmalted barley. The unmalted barley plays prominently in the flavor profile of Talnua’s various whiskeys, as well as its house-made gins.
The Bourbon Cask & Stave Series Whiskey, specifically, is aged in former bourbon barrels for three years along with charred oak staves, giving it bright floral, new mown hay, and vanilla bean notes, according to the distillery’s website. Patrick Miller, Talnua’s founder and master distiller, said by email that introducing the staves creates complexity in the flavor beyond what a single cask can offer.
“As a Colorado distillery rooted in tradition and driven by curiosity, it means a lot to be recognized among such respected peers. Honors like this don’t come around often, especially for smaller teams like ours, and we’re grateful,” Miller added in his statement.
Talnua also earned a gold medal for its American White Oak Cask Bottled in Bond whiskey, and a silver for its Old Saint’s Keep whiskey released in 2025. But it wasn’t the only local distiller to bring home awards.
Stranahan’s in Denver earned five medals total, including two double-gold, two gold and one silver; Pullman Distillery in Frisco brought home two bronze medals; Littleton’s Rocker Spirits collected two silvers; and Salida Distillery garnered one silver and one bronze.
St. Anthony Police are investigating after they were notified a child with a reported accidental gunshot wound to the head was brought to a hospital.
At about 6:40 p.m. Thursday, there was a 911 hang-up call in the area of the Equinox Apartments off Silver Lake Road in St. Anthony.
“Commotion could be heard in the background and the mention of the need for a hospital,” police said in a statement. “Officers arrived … within 2 minutes and were unable to locate the source of the call, any evidence of a crime, or a person in need of help.”
At 7:08 p.m., police were told about the child who’d been brought to the hospital.
Detectives interviewed two adults who were reported to be near the child when the gunshot happened. They told police it was in the Equinox Apartment parking lot inside a vehicle.
The child was admitted to the hospital. Information about the child’s age and condition weren’t immediately released.
Law enforcement gathered evidence at the hospital and the scene.
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Researchers described the case in a new study, saying he’s among the first to be successfully treated with a custom therapy that seeks to fix a tiny but critical error in his genetic code that kills half of affected infants. Though it may be a while before similar personalized treatments are available for others, doctors hope the technology can someday help the millions left behind even as genetic medicine has advanced because their conditions are so rare.
“This is the first step towards the use of gene editing therapies to treat a wide variety of rare genetic disorders for which there are currently no definitive medical treatments,” said Dr. Kiran Musunuru, a University of Pennsylvania gene editing expert who co-authored the study published Thursday in the New England Journal of Medicine.
The baby, KJ Muldoon of Clifton Heights, Pennsylvania, is one of 350 million people worldwide with rare diseases, most of which are genetic. He was diagnosed shortly after birth with severe CPS1 deficiency, estimated by some experts to affect around one in a million babies. Those infants lack an enzyme needed to help remove ammonia from the body, so it can build up in their blood and become toxic. A liver transplant is an option for some.
Knowing KJ’s odds, parents Kyle and Nicole Muldoon, both 34, worried they could lose him.
“We were, like, you know, weighing all the options, asking all the questions for either the liver transplant, which is invasive, or something that’s never been done before,” Nicole said.
“We prayed, we talked to people, we gathered information, and we eventually decided that this was the way we were going to go,” her husband added.
Within six months, the team at Children’s Hospital of Philadelphia and Penn Medicine, along with their partners, created a therapy designed to correct KJ’s faulty gene. They used CRISPR, the gene editing tool that won its inventors the Nobel Prize in 2020. Instead of cutting the DNA strand like the first CRISPR approaches, doctors employed a technique that flips the mutated DNA “letter” — also known as a base — to the correct type. Known as “base editing,” it reduces the risk of unintended genetic changes.
It’s “very exciting” that the team created the therapy so quickly, said gene therapy researcher Senthil Bhoopalan at St. Jude Children’s Research Hospital in Memphis, who wasn’t involved in the study. “This really sets the pace and the benchmark for such approaches.”
In February, KJ got his first IV infusion with the gene editing therapy, delivered through tiny fatty droplets called lipid nanoparticles that are taken up by liver cells.
While the room was abuzz with excitement that day, “he slept through the entire thing,” recalled study author Dr. Rebecca Ahrens-Nicklas, a gene therapy expert at CHOP.
After follow-up doses in March and April, KJ has been able to eat more normally and has recovered well from illnesses like colds, which can strain the body and exacerbate symptoms of CPS1. The 9 ½-month old also takes less medication.
Considering his poor prognosis earlier, “any time we see even the smallest milestone that he’s meeting – like a little wave or rolling over – that’s a big moment for us,” his mother said.
Still, researchers caution that it’s only been a few months. They’ll need to watch him for years.
“We’re still very much in the early stages of understanding what this medication may have done for KJ,” Ahrens-Nicklas said. “But every day, he’s showing us signs that he’s growing and thriving.”
In this photo provided by the Children’s Hospital of Philadelphia, KJ Muldoon, center, sits with his siblings after a follow up dose of an experimental gene editing treatment at the hospital in April 2025. (Chloe Dawson/Children’s Hospital of Philadelphia via AP)
In this photo provided by the Children’s Hospital of Philadelphia, Drs. Kiran Musunuru, left, and Rebecca Ahrens-Nicklas stand with KJ Muldoon, center, after a follow up dose of an experimental gene editing treatment at the hospital in April 2025. (Chloe Dawson/Children’s Hospital of Philadelphia via AP)
In this photo provided by the Children’s Hospital of Philadelphia, KJ Muldoon sits with his parents, Kyle and Nicole Muldoon, and his siblings after a follow up dose of an experimental gene editing treatment at the hospital in April 2025. (Chloe Dawson/Children’s Hospital of Philadelphia via AP)
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In this photo provided by the Children’s Hospital of Philadelphia, KJ Muldoon, center, sits with his siblings after a follow up dose of an experimental gene editing treatment at the hospital in April 2025. (Chloe Dawson/Children’s Hospital of Philadelphia via AP)
Researchers hope what they learn from KJ will help other rare disease patients.
Gene therapies, which can be extremely expensive to develop, generally target more common disorders in part for simple financial reasons: more patients mean potentially more sales, which can help pay the development costs and generate more profit. The first CRISPR therapy approved by the U.S. Food and Drug Administration, for example, treats sickle cell disease, a painful blood disorder affecting millions worldwide.
Musunuru said his team’s work — funded in part by the National Institutes of Health — showed that creating a custom treatment doesn’t have to be prohibitively expensive. The cost was “not far off” from the $800,000-plus for an average liver transplant and related care, he said.
“As we get better and better at making these therapies and shorten the time frame even more, economies of scale will kick in and I would expect the costs to come down,” Musunuru said.
Scientists also won’t have to redo all the initial work every time they create a customized therapy, Bhoopalan said, so this research “sets the stage” for treating other rare conditions.
Carlos Moraes, a neurology professor at the University of Miami who wasn’t involved with the study, said research like this opens the door to more advances.
“Once someone comes with a breakthrough like this, it will take no time” for other teams to apply the lessons and move forward, he said. “There are barriers, but I predict that they are going to be crossed in the next five to 10 years. Then the whole field will move as a block because we’re pretty much ready.”
The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.
“I think it’s time for us to just do it,” Trump told reporters as he wrapped a four-day visit to the Middle East.
Trump later told reporters after boarding Air Force One to begin the journey back to Washington that he may call Putin soon.
“He and I will meet, and I think we’ll solve it or maybe not,” Trump said. “At least we’ll know. And if we don’t solve it, it’ll be very interesting.”
President Donald Trump talks before signing guest book at the Abrahamic Family House, Friday, May 16, 2025, in Abu Dhabi, United Arab Emirates. (AP Photo/Alex Brandon)
Trump reiterated that he wasn’t surprised that Putin skipped out on the talks set for Friday in Turkey. Putin didn’t want to go because he’s not there, Trump said.
The Republican president added that he would hold a meeting with Putin “as soon as we can set it up.”
“I would actually leave here and go,” said Trump, who noted his daughter Tiffany just gave birth to her first child. “I do want to see my beautiful grandson.”
Ukrainian President Volodymyr Zelenskyy agreed to take part in the talks as Trump pressed for the leaders to find a solution to the war, ongoing since Russia’s February 2022 invasion of Ukraine. But Putin spurned the call to meet face-to-face with Zelenskyy.
Russian President Vladimir Putin speaks during a joint press statement with Malaysian Prime Minister Anwar Ibrahim at the Kremlin in Moscow, Russia, Wednesday, May 14, 2025. (Alexander Nemenov/Pool Photo via AP)
Trump has pressed both sides to quickly come to a war-ending agreement. Zelenskyy has agreed to an American plan for an initial 30-day halt to hostilities, but Russia has not signed on and has continued to strike at targets inside Ukraine.
Still, Russia and Ukraine were holding their first direct peace talks in three years Friday, gathering in Istanbul for negotiations. Officials and observers expect them to yield little immediate progress on stopping the more than 3-year-old war.
“He didn’t go, and I understand that,” Trump said. “We’re going to get it done. We got to get it done. Five thousand young people are being killed every single week on average, and we’re going to get it done.”
Trump on Thursday told reporters that a meeting between himself and Putin was crucial to breaking the deadlock.
“I don’t believe anything’s going to happen, whether you like it or not, until he and I get together,” Trump said. “But we’re going to have to get it solved because too many people are dying.”
