Vikings vs. Bears: What to know ahead of Week 11 matchup

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What to know when the Vikings host the Chicago Bears on Sunday afternoon:

Vikings vs. Bears
When: Noon Sunday
Where: U.S. Bank Stadium
TV: FOX / KMSP Ch. 9
Radio: KFAN
Line: Vikings -2.5
Over/Under: 48.5

Keys for the Vikings

— It shouldn’t be hard for the Vikings to move the chains against the Bears. They are going up against a defense that allows 375.7 yards of total offense per game. The only way the Vikings could get themselves into trouble is if quarterback J.J. McCarthy is careless with the ball. He has thrown six interceptions so far this season and is going up against a Bears defense that leads the league with 20 takeaways. It will be on McCarthy to keep the ball out of harm’s way this weekend.

Keys for the Bears

— All the Bears should be trying to do against the Vikings is keep the game close until the final minutes. They will enter the game as the underdog despite boasting a better record. It will be on the Bears to simply hang around by any means necessary. If they’re able to give quarterback Caleb Williams a chance to showcase his magic down the stretch, there’s a good chance he’ll get the job done. He currently leads the league in game-winning drives. It’s a big reason the Bears are currently in playoff position.

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Women’s hockey: No. 2 Gophers pull away from Bemidji State

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Minnesota scored four third-period goals to snap a 2-2 as the second-ranked Gophers beat Bemidji State on Friday at 3M Arena at Mariucci.

Six Gophers scored goals: Emma Kreisz, Sydney Morrow, Ava Lindsay, Jamie Nelson, Josefin Bouveng and Abbey Murphy as Minnesota improved to 11-2- overall and 7-2-0 in the WCHA.

Morrow scored short-handed to give the Gophers a 2-1 lead in the second period, and Lindsay’s goal put them up for good 5 minutes, 26 seconds into the third period.

Morgan Smith and Isa Goettl scored for Bemidji State (3-7-1, 1-7-1).

The teams meet again Saturday at Ridder Arena. Puck drop is set for 2 p.m.

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FDA adds strongest warning to Sarepta gene therapy linked to 2 patient deaths

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By MATTHEW PERRONE, Associated Press Health Writer

WASHINGTON (AP) — The Food and Drug Administration said Friday it will add a new warning and other limitations to a gene therapy for Duchenne’s muscular dystrophy that’s been linked to two patient deaths.

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The infused therapy from Sarepta Therapeutics will carry a boxed warning — the most serious type — alerting doctors and patients to the risk of potentially fatal liver failure with the treatment, the FDA said in a release.

The one-time therapy, Elevidys, has been under FDA scrutiny since the company reported the first of two deaths of teenage boys in March. Following a second death reported in June, the FDA briefly called for halting all shipments of the drug. But the agency quickly reversed course after facing pushback from patient families and libertarian activists close to President Donald Trump.

Elevidys is the first U.S.-approved gene therapy for Duchenne’s muscular dystrophy, a fatal muscle-wasting disease that affects boys and young men.

In addition to the boxed warning, the FDA is also limiting the drug’s approved use to patients who are 4 years old and up and can still walk. Previously the FDA had allowed the drug’s use in immobile patients, who generally have more advanced disease.

New labeling will also recommend weekly liver function monitoring for the first three months of treatment, as well as other precautionary steps.

Elevidys is Sarepta’s best-selling product and recent headwinds against the drug have weighed heavily on the company and its stock. In July, the Cambridge, Massachusetts-based company announced it would lay off 500 employees.

Sarepta Therapeutics Inc. shares rose 7.7% in trading after the FDA announcement, reflecting improved visibility for investors about the company’s outlook.

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.

US appeals court upholds hate crime convictions of 3 white men in 2020 killing of Ahmaud Arbery

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By RUSS BYNUM, Associated Press

SAVANNAH, Ga. (AP) — A federal appeals court on Friday upheld the hate crime convictions of three white men who chased Ahmaud Arbery through their Georgia subdivision with pickup trucks before one of them killed the running Black man with a shotgun.

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A three-judge panel of the 11th U.S. Circuit Court of Appeals took well over a year to rule after attorneys for the defendants urged the judges in March 2024 to overturn the case, arguing the men’s history of racist text messages and social media posts failed to prove they targeted Arbery because of his race.

Federal prosecutors used those posts and messages in 2022 to persuade a jury that Arbery’s killing was motivated by “pent-up racial anger.”

Even if the appeals judges had thrown out their hate-crime convictions, the trio faced no immediate reprieve from prison. That’s because they’re also serving life terms for murder after being convicted in a Georgia state court.

Father and son Greg and Travis McMichael armed themselves and used a pickup truck to pursue 25-year-old Arbery after spotting him running in their neighborhood just outside the port city of Brunswick on Feb. 23, 2020. A neighbor, William “Roddie” Bryan, joined the chase and recorded cellphone video of Travis McMichael shooting Arbery at close range.

More than two months passed without arrests, until Bryan’s graphic video of the killing leaked online. The Georgia Bureau of Investigation took over the case from local police as outrage over Arbery’s death became part of a national outcry over racial injustice. Charges soon followed.

All three men were convicted of murder by a state court in late 2021. After a second trial in U.S. District Court in early 2022, a jury found the trio guilty of hate crimes and attempted kidnapping.

Greg McMichael’s attorney, A.J. Balbo, declined to comment on the appellate ruling. Attorneys for Bryan and Travis McMichael did not immediately return phone and email messages.